After several years of incubation and internal validation, we are pleased to announce the publication of an article describing GenoSIGHT, an adaptive cytometry system, developed with a grant from the National Science Foundation (NSF Award#0963988). GenoSIGHT is an “intelligent” system capable of adapting the image acquisition process to the dynamics of the cells under observation. This closed-loop control of the imaging process results in faster and better experiments than when using an open-loop commonly found in commercially available software. The software was released open source using the Apache 2.0 license. It is available from SourceForge. The article entitled “Adaptive Imaging Cytometry to Estimate Parameters of Gene Networks Models in Systems and Synthetic Biology” was published by PLoS ONE on September 11, 2011. doi:10.1371/journal.pone.0107087.
We are now looking for collaborators who may be interested in using this software to characterize various genetic parts in E.coli, yeast, and possibly mammalian cells. Drop us a comment to suggest possible applications of this system that we may not have though of yet.