Last month, we presented our work on modeling the cell cycle using high-throughput yeast genetics at the fourth Gordon Research Conference on Synthetic Biology.
The poster presented (below) describes a hybrid approach in which we investigate a small number of genetic interactions (630) with an unprecedented number of biological replicates (up to 20) in order to better characterize mutant combinations that result in lethality. The poster was well-received by yeast geneticists, computer scientists who build gene network models, and researchers who are generally curious about high-throughput workflows. We plan to publish a paper describing our findings later this year.
To learn more about the conference, see the guest post we contributed on the PLOS Synthetic Biology Blog: https://blogs.plos.org/synbio/2019/08/12/meeting-report-gordon-research-conference-on-synthetic-biology/
To learn more about our work in high-throughput yeast genetics, visit our research page: https://peccoud.org/eukaryotic-cell-cycle/