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Home2019-06-26T21:21:01+00:00

DNA is the new silicon.

– Jean Peccoud

Today’s most pressing challenges are the result on an unsustainable reliance on synthetic chemistries. Synthetic biology will provide innovative paths to enduring health, food security, and sustainable energy. Traditional methods in biology are inadequate to face the magnitude and urgency of the solutions needed. These challenges call for a cultural revolution that leverages contributions from biology, engineering, manufacturing, and computer sciences to catalyze the emergence of creative solutions.

Our approach

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“Before working as a graduate student in Dr. Peccoud’s Lab I was an undergraduate student in his senior design group. Over the past year I have gained such valuable research experience and witnessed the vast amount of coordination it takes to run a high throughput lab. My time working for the Peccoud Lab was a big growth period. Every member of the lab is encouraging and passionate about what they are doing. Working in the lab was a challenge for me and the result of that was an improvement in my studies and research skills. I will miss being part of the Peccoud Lab and the amazing work that they do.”

SARAH CONDIO

“I was a visiting graduate student in Dr. Peccoud’s group for over a year. I had the opportunity to learn a great deal about a field in which I had no previous experience. Dr. Peccoud excels in putting together diverse groups of people to work on interdisciplinary projects. He is both dedicated and passionate about his work, and he inspires and energizes people in his group to do excellent work. I enjoyed my time at VBI and hope to work with Dr. Peccoud again in the future.”

REBECCA SHELTON

Latest News

Presenting Digital Signatures for DNA

A new project in the Peccoud Lab focuses on applying digital signatures to DNA in living organisms. Last week, postdoc Jenna Gallegos gave a presentation at the Synthetic Biology, Evolution, Engineering, and Design meeting in ScottsDale, Arizona describing this work. Abstract DNA molecules are frequently shared within the life sciences community, sometimes [...]

MinION: Optimizing a Sequencing Run

Adventures with the MinION Part III: Optimizing Protocols and Technology For Success As mentioned in previous posts (found here and here), optimization of this immature technology is one of the major hurdles users face.   In order to help others bypass the learning curve, we have laid out some of [...]

MinION: Learning Curve, Challenges, and Critiques

Adventures with the MinION II: Challenges and Drawbacks to the Novel Technology Oxford Nanopore Technology’s (ONT) MinION has garnered considerable excitement, for good reason.  It's suitable for labs on a limited budget, who work with DNA samples in the field, and who need long reads. These are all benefits that [...]

Research

  • Design and production of expression vectors
  • High throughput yeast genetics
  • Experimental validation of computational models
  • Cyberbiosecurity

Protocols

  • Molecular biology
  • DNA synthesis
  • DNA sequencing
  • Yeast genetics
  • Imaging protocols

Capabilities

  • Data management
  • Generating yeast mutants
  • High throughput phenotyping for model validation
  • Rationally design and synthesize optimized vectors
  • Build large datasets conducive to modeling via high throughput genetics

Goals

  • Experimentally validate computational models and software
  • Explore the connections between physical samples and their digital reference sequences
  • Develop fruitful collaborations with modelers and software developers
  • Leverage the similarities between computer languages and the genetic code for modular design of DNA constructs
  • Applying manufacturing practices and principles to life science workflows