GenomeWeb published a long article about the sustainability of bioinformatics infrastructures based on the GenoCAD transition into a commercial product. The articles describes the challenges of finding the right business model allowing the scientific community who depends on the tools to access it without restriction while at the same time generating enough revenue to ensure its maintenance and further developments. Other bioinformatics infrastructures have been exploring different options to generate revenue. KEGG is charging users interested in accessing their FTP server. The TAIR database explored different business models including corporate sponsorships and subscriptions. Read the complete article here: GenoFAB Mulls Commercialization Options for GenoCAD, Seeks Partners for Pilot Projects.

Let me know if you cannot access the site because it requires a subscription. I will send you a pdf version of the article.