gene synthesis

Improving DNA Manufacturing Through Standardization

Improving DNA Manufacturing Through Standardization

 

By framing gene synthesis as a manufacturing problem, it is possible to utilize common Industrial Engineering (IE) principles that have been applied to numerous macroscale systems in the burgeoning realm of DNA fabrication. These techniques have been successfully employed in an academic [...]

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This manuscript was submitted for presentation at IWBDA 2013. It was not accepted. The reviews we received are copied below. The manuscript will eventually be revised and published elsewhere. ----------------------- REVIEW 1 --------------------- PAPER: 11 TITLE: Improving DNA Manufacturing Through...

Discover how synthetic genes can further your research

Discover how synthetic genes can further your research

On August 1st at 9:00 am, we will host Dr Rafty from DNA2.0 for an exciting seminar on gene synthesis. More details about the seminar can be found below. Space is limited and registration strongly encouraged.   [contentblock id=9 img=gcb.png]

Development of Synthetic Flu Vaccines

An excellent video produced by SynBerc during the First Mammalian Synthetic Biology Workshop held at MIT in May 2013. [contentblock id=7 img=iframe.png]

Sequence verification of synthetic DNA by assembly of sequencing reads

Sequence verification of synthetic DNA by assembly of sequencing reads

Gene synthesis attempts to assemble user-defined DNA sequences with base-level precision. Verifying the sequences of construction intermediates and the final product of a gene synthesis project is a critical part of the workflow, yet one that has received the least...

NSF awards $1 million to improve the efficiency of DNA fabrication

BLACKSBURG, Va. July 25, 2012 The National Science Foundation (NSF) has awarded a three-year $999,531 grant to Virginia Tech to optimize the laboratory processes used to make custom DNA molecules with the tools and methods of industrial engineering. The interdisciplinary...

CloneQC: Lightweight Sequence Verification For Synthetic Biology

CloneQC: Lightweight Sequence Verification For Synthetic Biology

Article Summary Sequence verification is an important step in the Gene Synthesis process.  Creating a plasmid or chromosome from a series of smaller building blocks introduces many opportunities for error, so sequence verification as a quality control has relevance throughout...

What is Gene Synthesis?

What is Gene Synthesis?

This article explains what is gene synthesis, a combination of chemical and biological processes to produce synthetic DNA that does not exist in nature.  This technology transforming genetic engineering from a laborious art to an information-driven discipline. Although substantial advances have...

Gene Synthesis Demystified

The review on gene synthesis authored by Mike Czar is featured on the cover of Trends in Biotechnology. Read article.

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