sequencing

MinION: Oxford NanoPore’s DNA sequencing Innovation

Adventures with MinION Part I: Understanding ONT’s DNA sequencing technology The 50th anniversary of the historic double helix DNA model came three years after the completion of the Human Genome Project (HGP).  Providing industrialized methods of DNA sequencing, this project...

Sequence verification of synthetic DNA by assembly of sequencing reads

Sequence verification of synthetic DNA by assembly of sequencing reads

Gene synthesis attempts to assemble user-defined DNA sequences with base-level precision. Verifying the sequences of construction intermediates and the final product of a gene synthesis project is a critical part of the workflow, yet one that has received the least...

Next-generation DNA sequencing

Next-generation DNA sequencing

This article is an interesting review of how Next-Generation sequencing differs from traditional Sanger sequencing, along with the pros and cons of each approach.  Overall, the advantage of NextGen sequencing seems to be that it bypasses some of the traditional...