stochastic model

/Tag: stochastic model

Noisy foresight

By |2019-02-06T19:38:07+00:00January 12th, 2016|

Twenty years ago, I was just a boy with a crazy dream of building stochastic models of the noise affecting the expression of genes in living cells. Back in the 90s this idea sounded like an heresy. The dominant paradigm of the time was to consider that gene regulation was a qualitative and deterministic process [...]

Leave it to chance or not

By |2019-02-06T19:38:11+00:00September 29th, 2015|

Carolyn Beans wrote a blog post about our project to develop stochastic models of the regulatory network controlling cell division.  She was particularly interested in aspects of cell physiology that are affected by random events and how cells manage to remain healthy despite the vagaries of molecular interactions. Read her post on the NIGMS Biobeat [...]

Measurements modeling transcription noise makes the cover of Cell Cycle

By |2019-02-06T19:42:59+00:00October 7th, 2013|

The October issue of Cell Cycle includes an article reporting our efforts to measure and model the transcriptional noise affecting the the regulatory network controlling the cell cycle in the baker yeast (Saccharomyces cerevisiae). The journal cover page features an image derived from this work.   Cell Cycle. 2013 Sep 4;12(19). [Epub ahead of print] Measurement [...]