Last month, we presented our work on modeling the cell cycle using high-throughput yeast genetics at the fourth Gordon Research Conference on Synthetic Biology. The poster presented (below) describes a hybrid approach in which we investigate a small number of genetic interactions (630) with an unprecedented number of biological replicates (up to 20) in [...]
We just submitted a revised version of a manuscript describing the analysis of data collected using our GenoSIGHT software. The paper shows that this data can be used to estimate parameters of gene network models. This manuscript is under consideration with PLoS Computational Biology. I am relieved that we were able to complete these revisions. [...]
The October issue of Cell Cycle includes an article reporting our efforts to measure and model the transcriptional noise affecting the the regulatory network controlling the cell cycle in the baker yeast (Saccharomyces cerevisiae). The journal cover page features an image derived from this work. Cell Cycle. 2013 Sep 4;12(19). [Epub ahead of print] Measurement [...]
